MAGEA8-AS1

Across TCGA pan-cancer cohorts, MAGEA8-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MAGEA8-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MAGEA8-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MAGEA8-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and UCS show a favorable association.

COAD, ACC, and MESO are the cancer types where MAGEA8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.551	0.724	<.001	108	view →
ACC	DFS	Tertile	All	0.829	0.446	.014	56	view →
MESO	OS	Median	All	0.300	0.481	.007	55	view →
CHOL	OS	Tertile	All	0.200	0.863	<.001	48	view →
UCS	DFS	Tertile	III,IV	0.591	0.107	.002	44	view →
GBM	OS	Tertile	All	0.578	0.364	.003	35	view →
PAAD	DFS	Quartile	All	0.502	0.221	.010	23	view →
LUSC	OS	Tertile	All	0.809	0.704	.007	17	view →
DLBC	OS	Median	All	0.647	1.000	.013	16	view →
ESCA	DFS	Tertile	All	1.000	0.408	.010	15	view →
KICH	OS	Quartile	All	0.630	0.895	.012	12	view →
SARC	OS	Quartile	All	0.406	0.675	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MAGEA8-AS1–COAD (DFS)

Open the COAD breakdown →