MAGE family member A7, pseudogeneGenealiases: MAGE7 · MAGEA7
Q-omics provides the consensus-scored MAGEA7P profile across patient tissues and cancer cell-line models. MAGEA7P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, MAGEA7P is differentially expressed in 2, with the highest sampling consensus in BRCA. Additionally, MAGEA7P RNA expression shows 5,493 significant pathway-activity associations, with the highest sampling consensus in UCEC. Together, these results highlight STAD, BRCA, and UCEC as cancer lineages where MAGEA7P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MAGEA7P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MAGEA7P survival associations across molecular data types. MAGEA7P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MAGEA7P RNA expression–survival associations across cancer types. High MAGEA7P expression shows unfavorable associations in STAD, MESO, ESCA, LUSC, GBM and PCPG. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify STAD as the clearest survival context for MAGEA7P RNA expression.
This table summarizes MAGEA7P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for MAGEA7P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MAGEA7P shows lower tumor expression in BRCA and higher tumor expression in HNSC. The BRCA box plot shows higher MAGEA7P RNA expression in normal versus tumor tissue (log2 FC = −0.028, t-test p < 0.001).
This table shows molecular features associated with MAGEA7P in patient tissues and cancer cell lines. In patient samples, MAGEA7P shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.
