MAGEA4-AS1

Across TCGA pan-cancer cohorts, MAGEA4-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated MAGEA4-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher MAGEA4-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MAGEA4-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

KIRP, KIRC, and LIHC are the cancer types where MAGEA4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.221	0.717	<.001	150	view →
KIRC	DFS	Tertile	III,IV	0.366	0.672	<.001	144	view →
LIHC	OS	Tertile	All	0.465	0.713	<.001	81	view →
THCA	OS	Tertile	II,III,IV	0.646	0.924	<.001	57	view →
BRCA	DFS	Tertile	III,IV	0.728	0.897	<.001	54	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	48	view →
COAD	DFS	Tertile	II,III,IV	0.211	0.526	.005	33	view →
TGCT	DFS	Quartile	II,III,IV	0.684	1.000	.017	28	view →
STAD	DFS	Tertile	II,III,IV	0.285	0.453	.016	26	view →
PCPG	DFS	Tertile	All	0.482	0.897	<.001	21	view →
READ	DFS	Median	IV	0.347	0.744	.008	15	view →
UCEC	DFS	Tertile	All	0.513	0.691	.021	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

MAGEA4-AS1–KIRP (OS)

Open the KIRP breakdown →