Across TCGA patient cohorts, MAGEA3 protein abundance is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MAGEA3-associated genes across cancer lineages are GABRA3, MAGEA6, and KHNYN. Each is linked with MAGEA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEA3-to-partner and partner-to-MAGEA3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA3→partner) and Y-score (partner→MAGEA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GABRA3 →	+2.992	+2.367	<.001	.006	3	2
LUAD	MAGEA6 →	+5.372	+1.966	<.001	.007	2	3
LUAD	KHNYN →	-0.578	-1.514	<.001	.005	3	1
LUAD	GIP →	+0.732	+1.992	.003	<.001	3	1
LUAD	MGAT5B →	+2.520	+2.162	.006	.009	3	1
LUAD	ZNF280A →	+0.790	+2.164	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

Exploration

MAGEA3 survival (RNA) · tumor vs normal (RNA) · all MAGEA3 data types