Across TCGA cell cohorts, MAGEA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,721 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MAGEA3-associated GO terms across cancer lineages are Secondary piRNA processing, Positive regulation of telomere maintenance via telomerase, and Gamma-aminobutyric acid signaling pathway. Each is linked with MAGEA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAGEA3-to-partner and partner-to-MAGEA3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA3→partner) and Y-score (partner→MAGEA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Secondary piRNA processing →	+1.687	+3.514	<.001	.003	3	7
SKIN	Positive regulation of telomere maintenance via telomerase →	+0.065	+2.428	<.001	<.001	3	7
STOMACH	Gamma-aminobutyric acid signaling pathway →	-0.245	-3.364	.005	.002	2	8
LUNG_NSCLC_LUAD	Negative regulation of adaptive immune response →	-0.055	-2.633	.001	.003	3	6
BLOOD_Lymphoma	Synaptic transmission, GABAergic →	-0.160	-1.803	<.001	.002	3	6
BREAST	Membrane protein proteolysis →	+0.094	+2.480	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,721 associations by consensus.

Exploration

MAGEA3 survival (RNA) · tumor vs normal (RNA) · all MAGEA3 data types