Across TCGA cell cohorts, MAGEA3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAGEA3-associated genes across cancer lineages are BPIFB6 and RBMY1A1. Each is linked with MAGEA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA3-to-partner and partner-to-MAGEA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA3→partner) and Y-score (partner→MAGEA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
OVARY	RBMY1A1 →	+0.143	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

MAGEA3 survival (RNA) · tumor vs normal (RNA) · all MAGEA3 data types