MAGEA2B

Across TCGA patient cohorts, MAGEA2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,280 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAGEA2B-associated GO terms across cancer lineages are 'de novo' AMP biosynthetic process, Pseudouridine synthesis, and Positive regulation of natural killer cell mediated immune response to tumor cell. Each is linked with MAGEA2B in more than 7 cancer types. Because this analysis shows association rather than direction, both MAGEA2B-to-partner and partner-to-MAGEA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' AMP biosynthetic process grouped by MAGEA2B-low versus MAGEA2B-high in LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA2B→partner) and Y-score (partner→MAGEA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	'de novo' AMP biosynthetic process →	+0.051	+0.045	<.001	<.001	3	7
STAD	Pseudouridine synthesis →	+0.038	+0.089	<.001	.002	2	7
STAD	Positive regulation of natural killer cell mediated immune response to tumor cell →	+0.098	+0.105	<.001	<.001	3	6
STAD	Cellular respiration →	+0.043	+0.121	<.001	<.001	3	6
STAD	Metaphase chromosome alignment →	+0.044	+0.121	<.001	<.001	3	6
STAD	Nuclear membrane organization →	+0.039	+0.097	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,280 associations by consensus.

'de novo' AMP biosynthetic process by MAGEA2B expression — LUAD

Explore this box plot interactively →