MAGEA2B

Across TCGA cell cohorts, MAGEA2B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,427 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MAGEA2B-associated GO terms across cancer lineages are Negative regulation of adaptive immune response, Gamma-aminobutyric acid signaling pathway, and Positive regulation of telomere maintenance via telomere lengthening. Each is linked with MAGEA2B in more than 6 cancer types. Because this analysis shows association rather than direction, both MAGEA2B-to-partner and partner-to-MAGEA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of adaptive immune response grouped by MAGEA2B-low versus MAGEA2B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA2B→partner) and Y-score (partner→MAGEA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of adaptive immune response →	-0.143	-3.185	<.001	<.001	3	7
STOMACH	Gamma-aminobutyric acid signaling pathway →	-0.267	-3.052	.001	<.001	3	6
CNS	Positive regulation of telomere maintenance via telomere lengthening →	+0.061	+2.254	.001	<.001	3	6
STOMACH	Negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	-0.142	-3.279	<.001	<.001	3	6
SKIN	Nucleotide-sugar metabolic process →	+0.061	+3.075	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Oocyte growth →	+0.127	+2.072	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,427 associations by consensus.

Negative regulation of adaptive immune response by MAGEA2B expression — STOMACH

Explore this box plot interactively →