MAGEA2

Across TCGA patient cohorts, MAGEA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,818 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAGEA2-associated GO terms across cancer lineages are Protein localization to chromosome, centromeric region, DNA replication initiation, and Chromosome separation. Each is linked with MAGEA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAGEA2-to-partner and partner-to-MAGEA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome, centromeric region grouped by MAGEA2-low versus MAGEA2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA2→partner) and Y-score (partner→MAGEA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to chromosome, centromeric region →	+0.051	+0.146	<.001	<.001	3	8
LUAD	DNA replication initiation →	+0.050	+0.053	<.001	<.001	3	8
STAD	Chromosome separation →	+0.050	+0.179	<.001	<.001	3	7
LUAD	Mitotic sister chromatid separation →	+0.054	+0.064	<.001	<.001	3	7
STAD	Response to hydroxyurea →	+0.042	+0.132	<.001	<.001	3	7
STAD	Maintenance of centrosome location →	+0.058	+0.178	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,818 associations by consensus.

Protein localization to chromosome, centromeric region by MAGEA2 expression — STAD

Explore this box plot interactively →