MAGEA10

Across TCGA patient cohorts, MAGEA10 mutation is significantly associated with the RNA expression of many other genes, with 2,293 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA10-associated genes across cancer lineages are ATP6AP1L, DCP1A, and EIF4E. Each is linked with MAGEA10 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEA10-to-partner and partner-to-MAGEA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6AP1L grouped by MAGEA10-low versus MAGEA10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA10→partner) and Y-score (partner→MAGEA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP6AP1L →	+0.294	+1.874	.005	.002	3	3
UCEC	DCP1A →	+0.503	+3.111	<.001	<.001	3	2
UCEC	EIF4E →	+0.359	+1.638	.004	.005	3	2
UCEC	GUF1 →	+0.361	+2.949	.003	<.001	3	2
UCEC	GPATCH11 →	+0.415	+2.628	<.001	<.001	3	2
UCEC	RAD17 →	+0.422	+2.201	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,293 associations by consensus.

ATP6AP1L by MAGEA10 expression — UCEC

Explore this box plot interactively →