Across TCGA patient cohorts, MAFK protein abundance is significantly associated with the RNA expression of many other genes, with 1,517 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MAFK-associated genes across cancer lineages are IL13RA2, PLCD3, and LINC02471. Each is linked with MAFK in more than 1 cancer types. Because this analysis shows association rather than direction, both MAFK-to-partner and partner-to-MAFK results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFK→partner) and Y-score (partner→MAFK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IL13RA2 →	-0.937	-0.434	.001	.003	3	2
LUAD	PLCD3 →	+0.889	+0.602	<.001	<.001	3	2
LUAD	LINC02471 →	-0.640	-0.379	.006	.002	3	2
LUAD	OR5K2 →	-0.227	-0.429	.002	<.001	3	2
PDAC	RPSAP12 →	+0.472	+0.746	.009	.005	3	2
HNSC	VIM-AS1 →	-0.626	-0.854	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,517 associations by consensus.

Exploration

MAFK survival (RNA) · tumor vs normal (RNA) · all MAFK data types