Across TCGA patient cohorts, MAFK mutation is significantly associated with the RNA expression of many other genes, with 954 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAFK-associated genes across cancer lineages are MIR548AP, RN7SL813P, and VENTXP3. Each is linked with MAFK in more than 1 cancer types. Because this analysis shows association rather than direction, both MAFK-to-partner and partner-to-MAFK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFK→partner) and Y-score (partner→MAFK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR548AP →	+0.317	+8.055	<.001	.007	3	1
CESC	RN7SL813P →	+0.384	+5.103	<.001	.008	3	1
CESC	VENTXP3 →	+0.130	+5.812	<.001	.003	3	1
UCEC	IGHV3OR16-13 →	+0.626	+2.311	.002	.002	3	1
UCEC	MIR6500 →	+0.266	+2.674	.004	.006	3	1
UCEC	IGHV1OR21-1 →	+0.560	+2.443	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 954 associations by consensus.

Exploration

MAFK survival (RNA) · tumor vs normal (RNA) · all MAFK data types