Across TCGA patient cohorts, MAFK mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAFK-associated genes across cancer lineages are p62 Lck ligand, Annexin-1, and Caspase-7-cleavedD198. Each is linked with MAFK in more than 1 cancer types. Because this analysis shows association rather than direction, both MAFK-to-partner and partner-to-MAFK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFK→partner) and Y-score (partner→MAFK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.405	+3.331	.007	.005	3	1
UCEC	Annexin-1 →	+0.881	+3.321	<.001	.009	3	1
UCEC	Caspase-7-cleavedD198 →	+0.834	+2.584	.002	.011	3	1
UCEC	cIAP →	+0.176	+2.611	.005	.006	3	1
UCEC	Rad50 →	-0.371	-3.700	.001	.001	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

MAFK survival (RNA) · tumor vs normal (RNA) · all MAFK data types