Across TCGA patient cohorts, MAFG protein abundance is significantly associated with the RNA expression of many other genes, with 7,610 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAFG-associated genes across cancer lineages are DARS2, KHDC4, and MSI1. Each is linked with MAFG in more than 2 cancer types. Because this analysis shows association rather than direction, both MAFG-to-partner and partner-to-MAFG results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFG→partner) and Y-score (partner→MAFG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DARS2 →	+0.531	+0.644	<.001	<.001	3	3
HNSC	KHDC4 →	+0.502	+0.545	<.001	.001	3	3
BRCA	MSI1 →	+1.123	+0.318	<.001	.002	3	3
LSCC	MTHFD2 →	+0.576	+0.488	.001	<.001	3	3
HNSC	PGS1 →	+0.483	+0.472	<.001	<.001	3	3
LSCC	LINC02071 →	+0.202	+0.592	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,610 associations by consensus.

Exploration

MAFG survival (RNA) · tumor vs normal (RNA) · all MAFG data types