MAFG-DT

Across TCGA pan-cancer cohorts, MAFG-DT RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MAFG-DT data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MAFG-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MAFG-DT expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

BLCA, KIRC, and ACC are the cancer types where MAFG-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.252	0.464	<.001	138	view →
KIRC	OS	Tertile	All	0.544	0.733	<.001	130	view →
ACC	DFS	Median	All	0.215	0.674	<.001	102	view →
LIHC	OS	Median	All	0.693	0.864	<.001	73	view →
HNSC	OS	Tertile	IV	0.454	0.252	.003	30	view →
SARC	OS	Median	All	0.667	0.814	.001	26	view →
KIRP	OS	Median	II,III,IV	0.607	0.860	.001	24	view →
BRCA	DFS	Tertile	IV	0.814	0.275	.002	16	view →
THCA	DFS	Median	IV	0.435	0.870	<.001	15	view →
PRAD	DFS	Median	All	0.915	0.952	.014	12	view →
KICH	OS	Tertile	II,III,IV	1.000	0.462	.022	11	view →
UVM	DFS	Median	III,IV	0.853	0.494	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MAFG-DT–BLCA (DFS)

Open the BLCA breakdown →