Across TCGA patient cohorts, MAFF protein abundance is significantly associated with the RNA expression of many other genes, with 4,574 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAFF-associated genes across cancer lineages are FBP1, RPL32P1, and LINC00582. Each is linked with MAFF in more than 2 cancer types. Because this analysis shows association rather than direction, both MAFF-to-partner and partner-to-MAFF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFF→partner) and Y-score (partner→MAFF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FBP1 →	-1.418	-0.329	<.001	.003	3	3
HNSC	RPL32P1 →	-0.990	-0.379	.004	.008	3	3
HNSC	LINC00582 →	-0.774	-0.615	.006	<.001	3	3
OV	RPS27P16 →	+0.438	+0.537	.008	.004	3	2
BRCA	ROGDI →	-0.672	-0.327	<.001	<.001	3	2
BRCA	GAR1 →	+0.430	+0.356	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,574 associations by consensus.

Exploration

MAFF survival (RNA) · tumor vs normal (RNA) · all MAFF data types