Across TCGA cell cohorts, MAFF RNA expression is significantly associated with the RNA expression of many other genes, with 11,069 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAFF-associated genes across cancer lineages are PPP1R15A, PLK3, and LIF. Each is linked with MAFF in more than 13 cancer types. Because this analysis shows association rather than direction, both MAFF-to-partner and partner-to-MAFF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFF→partner) and Y-score (partner→MAFF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PPP1R15A →	+1.911	+2.143	<.001	<.001	3	14
SOFT_TISSUE	PLK3 →	+1.500	+1.738	<.001	<.001	3	13
LUNG_NSCLC_LUSC	LIF →	+3.278	+1.491	.002	.003	2	14
OESOPHAGUS	PTPRH →	+2.092	+1.344	<.001	<.001	2	14
UPPER_AERODIGESTIVE_TRACT	DUSP5 →	+2.811	+1.597	<.001	<.001	3	13
BONE	TMEM184B →	+1.182	+2.523	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,069 associations by consensus.

Exploration

MAFF survival (RNA) · tumor vs normal (RNA) · all MAFF data types