Across TCGA cell cohorts, MAFF RNA expression is significantly associated with the go_rna of many other GO terms, with 6,031 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAFF-associated GO terms across cancer lineages are Negative regulation of small GTPase mediated signal transduction, Regulation of epithelial cell differentiation, and Regulation of epidermal cell differentiation. Each is linked with MAFF in more than 13 cancer types. Because this analysis shows association rather than direction, both MAFF-to-partner and partner-to-MAFF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFF→partner) and Y-score (partner→MAFF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of small GTPase mediated signal transduction →	+0.091	+1.925	<.001	<.001	3	14
BONE	Regulation of epithelial cell differentiation →	+0.087	+2.096	<.001	<.001	3	14
LUNG_SCLC	Regulation of epidermal cell differentiation →	+0.091	+1.518	<.001	<.001	3	13
LIVER	Establishment of skin barrier →	+0.255	+1.647	.005	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of ERK1 and ERK2 cascade →	+0.095	+1.618	<.001	<.001	3	12
BREAST	Regulation of protein K48-linked ubiquitination →	+0.124	+1.801	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,031 associations by consensus.

Exploration

MAFF survival (RNA) · tumor vs normal (RNA) · all MAFF data types