MAF

Across TCGA patient cohorts, MAF protein abundance is significantly associated with the RNA expression of many other genes, with 4,399 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MAF-associated genes across cancer lineages are ECT2, CD248, and NRXN2. Each is linked with MAF in more than 2 cancer types. Because this analysis shows association rather than direction, both MAF-to-partner and partner-to-MAF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAF versus ECT2 in UCEC, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAF→partner) and Y-score (partner→MAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ECT2 →	-1.267	-1.361	.005	<.001	3	3
UCEC	CD248 →	+1.279	+1.200	<.001	.005	3	3
UCEC	NRXN2 →	+1.583	+1.647	.004	<.001	3	2
UCEC	ZNF451 →	-0.758	-1.533	.009	.004	3	2
LSCC	SMC4 →	-0.758	-0.404	.004	.005	3	2
UCEC	PDCD10 →	-1.358	-1.529	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,399 associations by consensus.

MAF vs ECT2 — UCEC

Explore this scatter interactively →