MAEL

Across TCGA patient cohorts, MAEL protein abundance is significantly associated with the protein abundance of many other proteins, with 49 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAEL-associated proteins across cancer lineages are GIT1_S362, RRP12, and ASCL2_S28. Each is linked with MAEL in more than 1 cancer types. Because this analysis shows association rather than direction, both MAEL-to-partner and partner-to-MAEL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAEL versus GIT1_S362 in BRCA, with a Pearson correlation of -0.63.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAEL→partner) and Y-score (partner→MAEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GIT1_S362 →	-1.307	-1.907	.001	.007	3	1
BRCA	RRP12 →	-0.612	-1.087	.002	.003	3	1
BRCA	ASCL2_S28 →	+1.827	+2.110	<.001	.003	2	1
BRCA	CD36 →	+1.652	+1.563	<.001	.001	2	1
BRCA	TNKS1BP1_S437 →	+0.854	+2.033	.002	.004	2	1
BRCA	METTL16 →	-0.341	-1.451	<.001	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

MAEL vs GIT1_S362 — BRCA

Explore this scatter interactively →