MAEL

Across TCGA cell cohorts, MAEL RNA expression is significantly associated with the go_rna of many other GO terms, with 966 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MAEL-associated GO terms across cancer lineages are COPII vesicle coating, Positive regulation of heart rate, and Negative regulation of hematopoietic stem cell differentiation. Each is linked with MAEL in more than 4 cancer types. Because this analysis shows association rather than direction, both MAEL-to-partner and partner-to-MAEL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII vesicle coating grouped by MAEL-low versus MAEL-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAEL→partner) and Y-score (partner→MAEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	COPII vesicle coating →	+0.064	+0.060	<.001	.008	3	5
CNS	Positive regulation of heart rate →	-0.104	-0.276	.002	.003	3	4
OVARY	Negative regulation of hematopoietic stem cell differentiation →	+0.108	+0.148	.004	.005	2	5
STOMACH	Calcium ion import →	-0.061	-0.047	<.001	.002	3	4
BLOOD_Leukemia	Positive regulation of smooth muscle contraction →	-0.099	-0.205	.002	.009	3	4
CNS	T-helper 17 type immune response →	+0.068	+0.256	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 966 associations by consensus.

COPII vesicle coating by MAEL expression — SOFT_TISSUE

Explore this box plot interactively →