MADCAM1

Across TCGA cell cohorts, MADCAM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,223 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MADCAM1-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Methylglyoxal metabolic process, and Pre-mRNA catabolic process. Each is linked with MADCAM1 in more than 13 cancer types. Because this analysis shows association rather than direction, both MADCAM1-to-partner and partner-to-MADCAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by MADCAM1-low versus MADCAM1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MADCAM1→partner) and Y-score (partner→MADCAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Calcium-independent cell-matrix adhesion →	+0.232	+0.428	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Methylglyoxal metabolic process →	+0.132	+0.348	<.001	.006	3	14
BONE	Pre-mRNA catabolic process →	+0.211	+0.407	<.001	<.001	3	13
SKIN	Methylglyoxal catabolic process →	+0.118	+0.306	<.001	<.001	3	13
KIDNEY	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.090	+0.468	<.001	<.001	2	13
KIDNEY	Electron transport coupled proton transport →	+0.090	+0.468	<.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,223 associations by consensus.

Calcium-independent cell-matrix adhesion by MADCAM1 expression — LARGE_INTESTINE

Explore this box plot interactively →