MACROH2A1

Across TCGA patient cohorts, MACROH2A1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,442 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MACROH2A1-associated genes across cancer lineages are FPR2, CD300A, and LILRB3. Each is linked with MACROH2A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MACROH2A1-to-partner and partner-to-MACROH2A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACROH2A1 versus FPR2 in COAD, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROH2A1→partner) and Y-score (partner→MACROH2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FPR2 →	-1.249	-0.412	<.001	<.001	3	6
UCEC	CD300A →	-1.007	-0.309	<.001	<.001	3	5
UCEC	LILRB3 →	-0.813	-0.292	<.001	<.001	3	5
COAD	DBF4 →	-0.686	-0.356	<.001	<.001	3	5
PDAC	FCAR →	-0.539	-0.252	<.001	<.001	3	5
UCEC	MRPL12 →	-0.672	-0.152	.005	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,442 associations by consensus.

MACROH2A1 vs FPR2 — COAD

Explore this scatter interactively →