MACROD2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MACROD2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,973 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MACROD2-associated genes across cancer lineages are RN7SL864P, AIMP1P1, and PACRG. Each is linked with MACROD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MACROD2-to-partner and partner-to-MACROD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACROD2 versus RN7SL864P in GBM, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROD2→partner) and Y-score (partner→MACROD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRN7SL864P →+1.118+0.840<.001<.00137
GBMAIMP1P1 →+1.142+0.881<.001<.00136
UCECPACRG →+1.033+0.713<.001<.00136
GBMRPS10P2 →+1.112+1.038<.001<.00136
GBMADGRB3 →+0.967+0.740<.001<.00135
GBMCNTN4 →+0.828+0.993.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,973 associations by consensus.

MACROD2 vs RN7SL864P — GBM

Per-sample scatter of MACROD2 vs RN7SL864P in GBM (Pearson r = 0.71).

Explore this scatter interactively →

Exploration