MACO1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MACO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,703 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MACO1-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Vesicle cytoskeletal trafficking, and Regulation of mitophagy. Each is linked with MACO1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MACO1-to-partner and partner-to-MACO1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MACO1→partner) and Y-score (partner→MACO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASCOPII-coated vesicle cargo loading →+0.113+0.695<.001<.001311
LARGE_INTESTINEVesicle cytoskeletal trafficking →+0.049+0.457<.001.00339
UPPER_AERODIGESTIVE_TRACTRegulation of mitophagy →+0.082+0.703<.001<.00139
BREASTPositive regulation of GTPase activity →+0.061+0.785<.001<.00139
SOFT_TISSUEMacroautophagy →+0.044+0.769<.001<.00139
SKINPositive regulation of autophagy →+0.030+0.353.002.00239
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,703 associations by consensus.

Exploration