MAB21L4

Across TCGA patient cohorts, MAB21L4 mutation is significantly associated with the RNA expression of many other genes, with 947 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAB21L4-associated genes across cancer lineages are DLAT, ENTR1, and RCCD1. Each is linked with MAB21L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAB21L4-to-partner and partner-to-MAB21L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DLAT grouped by MAB21L4-low versus MAB21L4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAB21L4→partner) and Y-score (partner→MAB21L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DLAT →	+0.616	+2.700	.005	.006	3	2
UCEC	ENTR1 →	+0.606	+3.480	<.001	.002	3	2
UCEC	RCCD1 →	+0.441	+3.828	.006	<.001	3	2
UCEC	AP3D1 →	+0.612	+3.592	<.001	.001	3	2
UCEC	KARS1 →	+0.464	+3.346	.003	.005	3	2
UCEC	PKM →	+0.609	+3.329	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 947 associations by consensus.

DLAT by MAB21L4 expression — UCEC

Explore this box plot interactively →