MAB21L3

Across TCGA patient cohorts, MAB21L3 mutation is significantly associated with the RNA expression of many other genes, with 653 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAB21L3-associated genes across cancer lineages are RNU6-1252P, HNRNPDP2, and RNU5E-8P. Each is linked with MAB21L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAB21L3-to-partner and partner-to-MAB21L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1252P grouped by MAB21L3-low versus MAB21L3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAB21L3→partner) and Y-score (partner→MAB21L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-1252P →	+0.426	+7.731	<.001	.009	3	2
BRCA	HNRNPDP2 →	+0.119	+8.471	<.001	.005	3	2
SKCM	RNU5E-8P →	+0.425	+2.278	.003	.006	3	2
SKCM	RNU1-34P →	+0.076	+4.025	<.001	.007	3	2
SKCM	RN7SKP186 →	+0.074	+3.034	<.001	.008	3	2
SKCM	NCLP1 →	+0.095	+3.276	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 653 associations by consensus.

RNU6-1252P by MAB21L3 expression — BRCA

Explore this box plot interactively →