MAB21L2

Across TCGA cell cohorts, MAB21L2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAB21L2-associated genes across cancer lineages are OR51T1, GSG1L2, and BANF2. Each is linked with MAB21L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAB21L2-to-partner and partner-to-MAB21L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by MAB21L2-low versus MAB21L2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAB21L2→partner) and Y-score (partner→MAB21L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
BLOOD_Lymphoma	BANF2 →	+0.035	+4.643	.003	.005	3	1
BLOOD_Lymphoma	HIGD1C →	+0.168	+4.714	<.001	.002	3	1
LARGE_INTESTINE	IAPP →	+0.267	+2.643	.003	.007	3	1
LARGE_INTESTINE	KLHDC7B →	+0.429	+3.485	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR51T1 by MAB21L2 expression — BLOOD_Leukemia

Explore this box plot interactively →