Across TCGA pan-cancer cohorts, M6PR Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated M6PR data layer compared with 20 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher M6PR Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated M6PR expression acts as an unfavorable survival marker.
STAD and PRAD are the cancer types where M6PR Mutation most reproducibly stratifies survival.