M6PR

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, M6PR RNA expression is significantly associated with the RNA expression of many other genes, with 18,748 significant associations in total. ACC shows the largest number of these associations.

The most reproducible M6PR-associated genes across cancer lineages are TXNDC5, TRAM2, and TFIP11. Each is linked with M6PR in more than 33 cancer types. Because this analysis shows association rather than direction, both M6PR-to-partner and partner-to-M6PR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, M6PR versus TXNDC5 in DLBC, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (M6PR→partner) and Y-score (partner→M6PR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
DLBCTXNDC5 →+1.831+1.514<.001<.001334
DLBCTRAM2 →+1.590+1.300<.001<.001334
ACCTFIP11 →+0.951+1.177<.001<.001333
THYMEIF3L →+1.666+1.426<.001<.001333
DLBCHMGXB4 →+1.598+1.558<.001<.001333
DLBCEP300 →+2.346+1.710<.001<.001333
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,748 associations by consensus.

M6PR vs TXNDC5 — DLBC

Per-sample scatter of M6PR vs TXNDC5 in DLBC (Pearson r = 0.82).

Explore this scatter interactively →

Exploration