LZTS3

Across TCGA patient cohorts, LZTS3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,011 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LZTS3-associated genes across cancer lineages are ST6GALNAC1, HAS3, and CADM4. Each is linked with LZTS3 in more than 3 cancer types. Because this analysis shows association rather than direction, both LZTS3-to-partner and partner-to-LZTS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LZTS3 versus ST6GALNAC1 in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LZTS3→partner) and Y-score (partner→LZTS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ST6GALNAC1 →	+1.339	+0.456	<.001	<.001	3	4
LSCC	HAS3 →	-1.209	-0.338	<.001	.002	3	3
LUAD	CADM4 →	+0.777	+0.406	<.001	.001	3	3
PDAC	PON2 →	+0.660	+0.605	<.001	.003	3	3
GBM	ARHGAP21 →	+0.394	+0.314	.003	.002	3	3
GBM	SERINC1 →	+0.379	+0.364	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,011 associations by consensus.

LZTS3 vs ST6GALNAC1 — LSCC

Explore this scatter interactively →