LYVE1

Across TCGA patient cohorts, LYVE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,707 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LYVE1-associated proteins across cancer lineages are APCS, SYNPO2, and TMOD1. Each is linked with LYVE1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LYVE1-to-partner and partner-to-LYVE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYVE1 versus APCS in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYVE1→partner) and Y-score (partner→LYVE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APCS →	+1.009	+1.237	<.001	<.001	3	10
UCEC	SYNPO2 →	+1.002	+0.822	<.001	<.001	3	10
UCEC	TMOD1 →	+0.844	+1.076	<.001	<.001	3	9
OV	NID2 →	+0.476	+0.867	<.001	<.001	3	9
BRCA	OGN →	+1.220	+1.264	<.001	<.001	3	9
CCRCC	OLFML1 →	+0.948	+0.921	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,707 associations by consensus.

LYVE1 vs APCS — BRCA

Explore this scatter interactively →