LYSMD1

Across TCGA patient cohorts, LYSMD1 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYSMD1-associated genes across cancer lineages are Epithelial cells, Preadipocytes, and lymphatic Endothelial cells. Each is linked with LYSMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYSMD1-to-partner and partner-to-LYSMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by LYSMD1-low versus LYSMD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYSMD1→partner) and Y-score (partner→LYSMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.083	-2.321	.021	.036	3	2
COAD	Preadipocytes →	+0.050	+4.754	.001	.003	3	1
UCEC	lymphatic Endothelial cells →	-0.027	-3.405	.025	.005	3	1
UCEC	mv Endothelial cells →	-0.028	-3.169	.020	.019	3	1
UCEC	Basophils →	+0.223	+2.321	.009	.036	3	1
UCEC	pDC →	+0.056	+2.332	.022	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Epithelial cells by LYSMD1 expression — UCEC

Explore this box plot interactively →