LYSMD1

Across TCGA cell cohorts, LYSMD1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LYSMD1-associated genes across cancer lineages are VCX2, KIR3DL3, and APOC4. Each is linked with LYSMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYSMD1-to-partner and partner-to-LYSMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VCX2 grouped by LYSMD1-low versus LYSMD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYSMD1→partner) and Y-score (partner→LYSMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VCX2 →	+1.507	+4.415	<.001	.007	3	1
LARGE_INTESTINE	KIR3DL3 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	APOC4 →	+0.101	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

VCX2 by LYSMD1 expression — LARGE_INTESTINE

Explore this box plot interactively →