LYPLA2P3

Across TCGA pan-cancer cohorts, LYPLA2P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LYPLA2P3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LYPLA2P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LYPLA2P3 is over-expressed in tumor.

KIRC and KIRP are the cancer types where LYPLA2P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LYPLA2P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.325	<.001	9	view →
KIRP	All	All	+0.095	.008	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LYPLA2P3–KIRC

Open the KIRC breakdown →