Across TCGA patient cohorts, LYPLA2P1 mutation is significantly associated with the RNA expression of many other genes, with 93 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LYPLA2P1-associated genes across cancer lineages are NCAPGP2, TUBB4BP1, and GCSHP2. Each is linked with LYPLA2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPLA2P1-to-partner and partner-to-LYPLA2P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPLA2P1→partner) and Y-score (partner→LYPLA2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	NCAPGP2 →	+0.156	+4.883	<.001	.002	3	2
COAD	TUBB4BP1 →	+0.280	+4.917	<.001	.003	3	2
COAD	GCSHP2 →	+0.127	+4.392	<.001	.006	3	2
BLCA	GRPEL2P3 →	+0.071	+5.444	<.001	.002	3	2
BLCA	USP12PY →	+0.066	+4.685	<.001	.007	3	2
BLCA	RNU7-74P →	+0.758	+6.307	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 93 associations by consensus.

Exploration

LYPLA2P1 survival (RNA) · tumor vs normal (RNA) · all LYPLA2P1 data types