LYPLA1P2

Across TCGA patient cohorts, LYPLA1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,709 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LYPLA1P2-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Small nucleolar ribonucleoprotein complex assembly, and Positive regulation of mRNA metabolic process. Each is linked with LYPLA1P2 in more than 13 cancer types. Because this analysis shows association rather than direction, both LYPLA1P2-to-partner and partner-to-LYPLA1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by LYPLA1P2-low versus LYPLA1P2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPLA1P2→partner) and Y-score (partner→LYPLA1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	mRNA alternative polyadenylation →	+0.051	+0.139	.001	.002	3	14
THYM	Small nucleolar ribonucleoprotein complex assembly →	+0.052	+0.038	<.001	.001	2	14
UCS	Positive regulation of mRNA metabolic process →	+0.048	+0.162	<.001	.001	3	13
THYM	Vesicle targeting →	+0.044	+0.041	.005	.002	3	12
UCS	Protein modification by small protein removal →	+0.053	+0.172	<.001	<.001	3	12
UCS	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.055	+0.214	<.001	.002	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,709 associations by consensus.

mRNA alternative polyadenylation by LYPLA1P2 expression — ESCA

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