LYPLA1P2

Across TCGA pan-cancer cohorts, LYPLA1P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LYPLA1P2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LYPLA1P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LYPLA1P2 is over-expressed in tumor, although a few such as KIRC and ESCA show the opposite, repressed pattern.

BRCA, KIRC, and ESCA are the cancer types where LYPLA1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LYPLA1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.021	.005	4	view →
KIRC	All	All	−0.013	.012	4	view →
ESCA	All	All	−0.087	.046	1	view →
THCA	All	All	−0.010	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LYPLA1P2–BRCA

Open the BRCA breakdown →