Across TCGA patient cohorts, LYPD6 mutation is significantly associated with the RNA expression of many other genes, with 2,688 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYPD6-associated genes across cancer lineages are RNA5SP432, RNU6-839P, and RN7SL248P. Each is linked with LYPD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD6-to-partner and partner-to-LYPD6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD6→partner) and Y-score (partner→LYPD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP432 →	+0.329	+5.539	<.001	.004	3	2
BLCA	RNU6-839P →	+0.313	+7.640	<.001	.009	3	2
UCEC	RN7SL248P →	+0.051	+2.915	<.001	.007	3	2
SKCM	SIGLEC27P →	+0.043	+4.671	<.001	.004	3	2
SKCM	SULT6B1 →	+0.080	+4.206	<.001	.001	3	1
SKCM	IL9 →	+0.255	+3.622	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,688 associations by consensus.

Exploration

LYPD6 survival (RNA) · tumor vs normal (RNA) · all LYPD6 data types