Across TCGA patient cohorts, LYPD2 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYPD2-associated genes across cancer lineages are NDUFA3P3, OR2M4, and OR14C36. Each is linked with LYPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD2-to-partner and partner-to-LYPD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD2→partner) and Y-score (partner→LYPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFA3P3 →	+0.549	+5.003	<.001	.002	3	2
UCEC	OR2M4 →	+0.198	+5.146	<.001	.001	3	1
UCEC	OR14C36 →	+0.083	+5.335	.005	.003	3	1
COAD	RNU6-1017P →	+0.289	+4.516	.004	.009	3	1
COAD	TRAJ11 →	+0.936	+4.543	.001	.005	3	1
COAD	OR2W2P →	+0.041	+5.122	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

LYPD2 survival (RNA) · tumor vs normal (RNA) · all LYPD2 data types