LYG2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LYG2 mutation is significantly associated with the RNA expression of many other genes, with 566 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYG2-associated genes across cancer lineages are RN7SL237P, MIR4510, and NF1P10. Each is linked with LYG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYG2-to-partner and partner-to-LYG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYG2→partner) and Y-score (partner→LYG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL237P →+0.146+5.418<.001.00532
CESCMIR4510 →+0.403+6.342<.001.00132
CESCNF1P10 →+0.137+6.569.001.00132
STADFAM41AY1 →+0.098+6.070<.001.00232
BRCAUQCRC2P1 →+0.071+5.045<.001.00932
UCECRNA5SP420 →+0.662+2.604<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 566 associations by consensus.

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