LYARP1

Across TCGA pan-cancer cohorts, LYARP1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LYARP1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher LYARP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LYARP1 expression acts as an unfavorable survival marker.

BLCA, LUAD, and KIRP are the cancer types where LYARP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	III,IV	0.240	0.488	.001	60	view →
LUAD	OS	Tertile	III,IV	0.267	0.666	.025	54	view →
KIRP	OS	Tertile	All	0.277	0.724	<.001	48	view →
DLBC	DFS	Tertile	III,IV	0.070	0.765	.002	46	view →
HNSC	OS	Tertile	II,III,IV	0.381	0.717	<.001	42	view →
THCA	DFS	Tertile	IV	0.361	0.866	.001	36	view →
OV	OS	Tertile	IV	0.059	0.759	.006	36	view →
UVM	OS	Tertile	III,IV	0.037	0.815	<.001	36	view →
MESO	OS	Tertile	II,III,IV	0.195	0.577	.023	27	view →
TGCT	OS	Tertile	II,III,IV	0.670	1.000	.005	18	view →
READ	OS	Tertile	IV	0.077	1.000	.014	18	view →
LUSC	OS	Tertile	All	0.579	0.766	.045	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LYARP1–BLCA (DFS)

Open the BLCA breakdown →