Across TCGA pan-cancer cohorts, LYARP1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LYARP1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LYARP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LYARP1 is over-expressed in tumor.
KIRP are the cancer types where LYARP1 tumor–normal differential expression is most reproducible.