LY75

Across TCGA patient cohorts, LY75 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,954 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LY75-associated proteins across cancer lineages are PSMB5, PTPN7, and ARHGAP9_S113. Each is linked with LY75 in more than 5 cancer types. Because this analysis shows association rather than direction, both LY75-to-partner and partner-to-LY75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LY75 versus PSMB5 in LSCC, with a Pearson correlation of -0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LY75→partner) and Y-score (partner→LY75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSMB5 →	-0.524	-0.639	<.001	<.001	3	6
CCRCC	PTPN7 →	+0.562	+0.737	<.001	<.001	3	6
GBM	ARHGAP9_S113 →	+0.754	+0.643	<.001	.002	3	6
UCEC	FYB1_S225 →	+0.657	+1.269	<.001	<.001	3	6
BRCA	PSMB10 →	+0.495	+0.889	<.001	<.001	3	6
GBM	PTPN6 →	+0.553	+0.403	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,954 associations by consensus.

LY75 vs PSMB5 — LSCC

Explore this scatter interactively →