LY75

Across TCGA patient cohorts, LY75 protein abundance is significantly associated with the RNA expression of many other genes, with 4,485 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LY75-associated genes across cancer lineages are CFAP92, DLX4, and SEMA3B. Each is linked with LY75 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY75-to-partner and partner-to-LY75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LY75 versus CFAP92 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY75→partner) and Y-score (partner→LY75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CFAP92 →	-0.584	-0.283	.002	.007	3	2
LSCC	DLX4 →	-0.688	-0.503	<.001	<.001	3	2
UCEC	SEMA3B →	+1.318	+0.541	.004	.003	3	2
LSCC	LRTM1 →	-0.840	-0.418	.004	<.001	3	2
UCEC	TNFRSF14 →	+0.966	+0.499	.002	.001	3	2
LUAD	TFF2 →	+5.685	+0.663	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,485 associations by consensus.

LY75 vs CFAP92 — LSCC

Explore this scatter interactively →