LY75

Across TCGA cell cohorts, LY75 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,795 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LY75-associated GO terms across cancer lineages are Protein localization to cell surface, Basement membrane disassembly, and Regulation of Rho protein signal transduction. Each is linked with LY75 in more than 8 cancer types. Because this analysis shows association rather than direction, both LY75-to-partner and partner-to-LY75 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cell surface grouped by LY75-low versus LY75-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LY75→partner) and Y-score (partner→LY75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein localization to cell surface →	+0.124	+2.120	<.001	<.001	3	9
LARGE_INTESTINE	Basement membrane disassembly →	+1.440	+2.602	<.001	<.001	3	9
OVARY	Regulation of Rho protein signal transduction →	+0.089	+1.533	.001	<.001	3	9
OESOPHAGUS	Cortical actin cytoskeleton organization →	+0.141	+2.288	<.001	.001	3	9
OVARY	Positive regulation of leukocyte differentiation →	+0.081	+1.615	<.001	<.001	3	9
OVARY	Positive regulation of hemopoiesis →	+0.081	+1.615	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,795 associations by consensus.

Protein localization to cell surface by LY75 expression — PANCREAS

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