LY6K

Across TCGA patient cohorts, LY6K mutation is significantly associated with the RNA expression of many other genes, with 1,331 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LY6K-associated genes across cancer lineages are RNU6-13P, UBE2L2, and TMCC2-AS1. Each is linked with LY6K in more than 2 cancer types. Because this analysis shows association rather than direction, both LY6K-to-partner and partner-to-LY6K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-13P grouped by LY6K-low versus LY6K-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6K→partner) and Y-score (partner→LY6K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-13P →	+0.752	+4.308	<.001	.009	3	3
READ	UBE2L2 →	+0.091	+4.315	.001	.002	3	2
COAD	TMCC2-AS1 →	+0.192	+4.484	<.001	.002	3	2
READ	BAK1P2 →	+0.271	+4.142	<.001	.004	3	2
SKCM	MTND6P16 →	+0.027	+3.080	<.001	.006	3	2
COAD	RNU1-7P →	+0.506	+4.962	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,331 associations by consensus.

RNU6-13P by LY6K expression — COAD

Explore this box plot interactively →