LY6G6E

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LY6G6E Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated LY6G6E data layer compared with 19 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher LY6G6E Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LY6G6E expression acts as an unfavorable survival marker.

ESCA are the cancer types where LY6G6E Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSMedianAll0.2220.680.0316view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

LY6G6E–ESCA (OS)

Kaplan–Meier survival curve for LY6G6E mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration