Across TCGA pan-cancer cohorts, LY6G6E Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated LY6G6E data layer compared with 19 for mass-spec protein.
The strongest signal is observed in esophageal carcinoma (ESCA), where higher LY6G6E Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LY6G6E expression acts as an unfavorable survival marker.
ESCA are the cancer types where LY6G6E Mutation most reproducibly stratifies survival.