LY6G6E

Across TCGA patient cohorts, LY6G6E mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. COAD shows the largest number of these associations.

The most reproducible LY6G6E-associated genes across cancer lineages are RNU6-13P, LAP3P2, and RNA5SP205. Each is linked with LY6G6E in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6G6E-to-partner and partner-to-LY6G6E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-13P grouped by LY6G6E-low versus LY6G6E-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G6E→partner) and Y-score (partner→LY6G6E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-13P →	+0.549	+5.893	<.001	.002	3	2
COAD	LAP3P2 →	+0.064	+5.145	<.001	.007	3	2
UCEC	RNA5SP205 →	+0.607	+5.852	<.001	.003	3	1
UCEC	RFKP1 →	+0.226	+5.242	.001	.007	3	1
UCEC	GOLGA6L11P →	+0.075	+6.877	<.001	<.001	3	1
UCEC	LINC01706 →	+0.121	+5.621	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

RNU6-13P by LY6G6E expression — COAD

Explore this box plot interactively →