Across TCGA pan-cancer cohorts, LY6G6C mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LY6G6C data layer compared with 26 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LY6G6C mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LY6G6C expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC and HNSC are the cancer types where LY6G6C mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	1.000	0.535	.049	4	view →
HNSC	DFS	Median	All	1.000	0.929	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: LY6G6C tumor-vs-normal RNA expression · all LY6G6C data types